Dennis M. Hester, Ph.D.
Dennis Hester has been involved with product development for almost 30 years and has spent the last 20 years in San Diego working with a broad range of therapeutic agents, formulation technologies and routes of administration. Dennis’ experience spans small molecule solid oral therapeutics, a broad range of inhalation formulations, and peptide, protein and cell based sterile injectable products, for use in a number of indications including diabetes, infectious diseases and oncology. Dr. Hester has an impressive track record of successfully leading programs into, and through, clinical development resulting in launch readiness and/or commercial sales. He has contributed to over two dozen INDs and the approval of six commercial products with a number of compounds presently in late stage clinical development.
Dr. Hester is currently Calidi Biotherapeutic’s Senior Vice President, Technical Operations, with responsibilities for Regulatory Affairs, Quality Assurance, and Technical Operations including Chemistry, Manufacturing and Controls (CMC). Prior to joining Calidi, Dr. Hester held leadership roles at a number of San Diego companies including Vice President, Product Development and Head of CMC at Mirati Therapeutics, Senior Director, Pharmaceutical Sciences and Head of CMC at Aragon Pharmaceuticals and Director, Pharmaceutical Development and Head of CMC at Intellikine, Inc. Additionally, Dennis obtained extensive biologics experience while working at Nektar Therapeutics, Amylin Pharmaceuticals and other companies as a full time employee or as a consultant.
Dr. Hester holds a Ph.D. in Physical Chemistry from the University of Southern California, an American Chemical Society Accredited Bachelor of Science degree in Chemistry from the United States Air Force Academy, and is an inventor on seven issued patents.